We are pleased to announce the publication of our latest research in Translational Stroke Research, entitled “Circulating Microglia-Derived Extracellular Vesicles Predict Recovery After Rehabilitation in Stroke Survivors.”
This study explores whether a simple blood sample can provide meaningful insights into recovery following stroke. Our research focuses on extracellular vesicles released by brain cells, particularly microglia, that can circulate in the bloodstream and carry important biological signals.
Our findings indicate that these vesicles may serve as valuable indicators not only of brain injury but also of active repair and regeneration processes. By combining these biological markers with advanced machine-learning techniques, we demonstrate a promising step toward more objective and personalized approaches to stroke rehabilitation.
This study is the result of a remarkable joint effort between bench-side and bed-side research units of Fondazione Don Carlo Gnocchi.
Starting from the design of the clinical trial (EXO4STROKE), we have reached concrete results which are now available for reading of other researchers working in the field and laid the basis for the PRISMA project.