Head of the Laboratory
Marzia Bedoni received her MSc degree in Biological Sciences in 2004 and her PhD degree in Morphological Science in 2007 (University of Milan). From 2007 to 2010 she carried out her Post-Doctorate at the Laboratory of Nanomedicine and Biophotonics (LABION) of FDG granted by the Cariplo Foundation, Seed Capital and Seventh Framework Programme. From January 2011 she is permanent researcher in FDG. During her research activity at LABION she has worked on multiple project: i) nano-biophotonics for the characterisation of exosomes as regenerative rehabilitation markers; ii) biophotonics application for diagnosis and therapy monitoring in neurodegenerative diseases (Alzheimer’s disease and Amyotrophic Lateral Sclerosis), skin diseases (psoriasis, cancer), leukemia and; iii) nanoparticles toxicity on human skin biology; iv) biocompatibility in transdermal drug delivery and dry electrodes devices. From 2007 she is also lecturer in Human Anatomy for the Faculty of Medicine and Surgery at the University of Milan. She received some awards during international congresses for her research studies. She is author of several papers published in peer-reviewed scientific journals , abstracts for national and international congresses and she is also co-inventor of 4 patents. She is board member of the “Society for Cutaneous Ultrastructure Research (SCUR)”, and ordinary member of the “European Society of Dermatological Research” and the “Italian Society of Human Anatomy”. She is involved in several national and international projects.
Alice Gualerzi received her Master’s degree in Biology applied to biomedical research in 2009 and her PhD degree in Morphological Sciences in 2013 at the University of Milan, focusing her research on the morphological analysis of skin and oral mucosa after exposure to exogenous stimuli in a 3D culture model. In 2012 she collaborated for six months as Junior Research Specialist with Dr. Chia-Ling Tu the University of California San Francisco and she was later granted with a postdoctoral scholarship funded by Sardegna Ricerche to work at BT (Biomedical Tissues) srl c/o Parco scientifico e tecnologico Polaris (Pula, CA) in the field of cardiovascular tissue engineering, regenerative medicine, and nanotoxicity. She joined LABION in 2014 and the main focuses of her research are: i) biophotonic characterization of extracellular vesicles from mesenchymal stem cells to be used as regenerative agents and plasma exosomes as diagnostic and prognostic biomarkers for regenerative rehabilitation; (ii) Raman spectroscopy for the characterization of cells and tissues in health, pathology and for nanotoxicology purposes. She is author of several papers published in peer-reviewed scientific journals and of several abstracts for national and international congresses.
Silvia Picciolini graduated in pharmaceutical chemistry and technologies (CTF) at the University of Milan on March 2014. She spent one year at FDG doing research experience for her experimental thesis in collaboration with a spin off of the Joint Research Centre (Ispra) aimed at the optimization of nanohole arrays as solid SERS substrates for the detection of genetic biomarkers of acute myeloid leukemia (AML), in order to evaluate the minimal residual disease. She was granted with an AXA scholarship for the Raman analysis of lipids in the blood of Alzheimer’s patients. She is currently Phd student at LABION working on a project aimed at the detection and characterization of neuronal exosomes from human plasma, in order to identify their role in the pathogenesis of Alzheimer’s disease (AD). In particular, the intent is to design a SPRi based biosensor for the simultaneous detection of these multiple complex circulating biomarkers using an extremely limited amount of peripheral blood. She is co-author of 7 publications in international peer-reviewed journals and of several abstracts of national and international conferences.
Andrea Sguassero received his Master’s degree in Industrial biotechnology at the University of Milan-Bicocca on November 2017.He made his experimental thesis at LABION working on the development of a biosensor based on surface plasmon resonance imaging (SPRi) for the sensitive and multiplexing detection of microRNAs involved in multiple sclerosis disease (MS). He is currently fellow researcher at FDG.
Furio Gramatica, designer and founder of LABION and responsible of the laboratory until 2017, he is currently Head of the Innovation Unit at Don Gnocchi Foundation. For five years he served as Director of the Biomedical Technology Department “Polo Tecnologico” in the same Foundation. Formerly, he spent several years at CERN (Geneva), at Italian Institute of Nuclear Physics and in high-technology companies, with R&D management roles. Dr. Gramatica is fellow professor of physics at Milan University Medical School, Chair of the Working Group Clinical Interface, Executive Board Member of the European Technology Platform of Nanomedicine, evaluator and reviewer of the European Commission and of Wellcome Trust.
Carlo Morasso joined LABION in 2011 after a period as post doctoral scientist at London Centre for Nanotechnology – UCL. Expert in nanotechnology and optical spectroscopies, he was member of the LABION team until 2017 focusing on the implementation of biosensing techniques and, in particular, on the use of plasmonic based systems, as new diagnostic tools for cancer and neurodegenerative diseases. During his research period at LABION he was PI of a Euronanomed granted project for the development of a SERS-based biosensor for the evaluation of minimal residual disease (InNaSERSS). He is currently working at Fondazione Maugeri.
Renzo Vanna worked at LABION as post-doc from 2012 to 2017. He joined FDG as young researcher starting to collaborate in a project aimed at the development of a SERS-based biosensor for the evaluation of minimal residual disease in acute myeloid leukemia (AML). During his research period at LABION he was PI of a Euronanomed granted project for the development of a SPRi miRNA array for the monitoring of Multiple Sclerosis evolution (NanoplasmiRNA). He is currently working at Fondazione Maugeri.
Dora Mehn worked at LABION as senior researcher from 2011 to 2014, acquiring experience in SERS, especially in the detection of genetic biomarkers using solid SERS-enhancer surfaces. She is currently working at Joint Research Centre (JRC).